Jeffrey Milbrandt


Milbrandt lab postdoc publishes paper on single cell RNAseq and morphine treatment

Posted by on Apr 24, 2018 in Blog |

Denis Avey, PhD, a postdoctoral researcher in the Milbrandt and Mitra labs, is first author on a newly-uploaded preprint article. The paper, “Single cell RNAseq uncovers a robust transcriptional response to morphine by oligodendrocytes” can be accessed via bioRxiv. Sumithra Sankararaman, a research scientist in the Mitra lab, Aldrin K. Y. Yim, a graduate student in the Milbrandt lab, Ruteja Barve, PhD, Instructor of Genetics, Robi D. Mitra, PhD, Associate Professor of Genetics and Alvin Goldfarb Distinguished Professor of Computational Biology, and Jeffrey Milbrandt, PhD, MD, Head of the Department of Genetics, are also authors on the paper. You can access the article...

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Kow Essuman and colleagues publish paper in Current Biology

Posted by on Jan 25, 2018 in Blog |

The Milbrandt lab had a paper published recently in Current Biology. The paper, “TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes,” shows that TIR domain proteins from both bacteria and archaea cleave NAD+ into nicotinamide and ADP-ribose (ADPR), with catalytic cleavage executed by a conserved glutamic acid. Kow Essuman, an M.D./Ph.D. student in the Milbrandt lab, is first author on the paper, with co-authors Dr. Daniel Summers, Dr. Yo Sasaki, Dr. Xianrong Mao, Aldrin Kay Yuen Yim, Dr. Jeff Milbrandt, the James S. McDonnell Professor of Genetics and head of the Department of Genetics, and Dr. Aaron DiAntonio, Alan A and Edith L Professor of Developmental Biology at Washington University in St. Louis. Read more about the paper...

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