Milbrandt and DiAntonio labs publish paper on gene therapy for peripheral nerve damage in mice

Posted by on Jan 16, 2019 in Blog |

The Milbrandt and DiAntonio labs had a paper published recently on gene therapy that blocks peripheral damage in mice. The paper, “Gene therapy targeting SARM1 blocks pathological axon degeneration in mice,” appears in a recent issue of the Journal of Experimental Medicine. Stefanie Geisler, M.D., an assistant professor of neurology at Washington University School of Medicine, is first author on the paper. Jeff Milbrandt, M.D., Ph.D., the James...

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Kow Essuman named a Spencer T. and Ann W. Olin Medical Science Fellow

Posted by on Jan 7, 2019 in Blog |

Kow Essuman, a graduate student in Dr. Jeff Milbrandt’s lab in The Department of Genetics at Washington University School of Medicine, was recently named a Spencer T. and Ann W. Olin Medical Science Fellow. The Olin award recognizes outstanding achievement in biomedical research and is given annually to less than five percent of graduating DBBS and MSTP students. Candidates are nominated by their mentors, and screened by their PhD...

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Milbrandt lab postdoc publishes paper on axon survival factors

Posted by on Aug 28, 2018 in Blog |

Daniel W. Summers, Ph.D., a postdoc in Dr. Jeff Milbrandt’s lab, recently had a paper published in PNAS. The paper, “Palmitoylation enables MAPK-dependent proteostasis of axon survival factors,” shows that intracellular location imparts sensitivity to distinct protein homeostasis networks, and inactivating multiple nodes in this protein homeostasis network confers maximal therapeutic potential in diseases of axon degeneration....

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Milbrandt lab researcher takes new position at Novartis

Posted by on Aug 8, 2018 in Blog |

Bryan McGill, an Instructor of Neurology at Washington University School of Medicine and a member of the Milbrandt lab, has taken a new position at Novartis. “It was a really difficult decision to leave Washington University. The deciding factor for me was the opportunity to work full-time on clinical research full-time investigating treatments for pediatric neurologic disorders,” he said. Bryan will be working as a medical director...

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Milbrandt lab publishes paper on Schwann cell O-GlcNAcylation

Posted by on Jul 16, 2018 in Blog |

The Milbrandt lab published a paper recently on Schwann cell O-GlcNAcylation. The paper, “Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN,” appears in PNAS. Sungsu Kim, an instructor in the Department of Genetics and a member of the Milbrandt lab, is first author on the paper. Read the abstract...

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Milbrandt lab welcomes rotation student researching SARM1 activation

Posted by on Jul 5, 2018 in Blog |

The Milbrandt lab recently welcomed Caitlin Dingwall for a rotation project.  Caitlin received a B.S. in Molecular and Cellular Biology with Honors from the University of Illinois at Urbana-Champaign in 2015. For her Honors thesis, she worked in the lab of Dr. Phillip Newmark where she pursued dual projects investigating the role of matrix metalloproteinases in stem cell homeostasis in the freshwater planarian Schmidtea mediterranea and...

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