Jeffrey Milbrandt


Kow Essuman and colleagues publish paper in Current Biology

Posted by on Jan 25, 2018 in Blog |

The Milbrandt lab had a paper published recently in Current Biology. The paper, “TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes,” shows that TIR domain proteins from both bacteria and archaea cleave NAD+ into nicotinamide and ADP-ribose (ADPR), with catalytic cleavage executed by a conserved glutamic acid. Kow Essuman, an M.D./Ph.D. student in the Milbrandt lab, is first author on the paper, with co-authors Dr. Daniel Summers, Dr. Yo Sasaki, Dr. Xianrong Mao, Aldrin Kay Yuen Yim, Dr. Jeff Milbrandt, the James S. McDonnell Professor of Genetics and head of the Department of Genetics, and Dr. Aaron DiAntonio, Alan A and Edith L Professor of Developmental Biology at Washington University in St. Louis. Read more about the paper...

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Jeff Milbrandt has paper published in PNAS

Posted by on May 18, 2017 in Blog |

Jeff Milbrandt recently had a paper published in PNAS, titled: “mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells.” Dr. Bogdan Beirowski, principal investigator at the Hunter James Kelly Research Institute at the State University of New York, is lead author on the paper. Keit Men Wong, a Ph.D. student at the State University of New York, and Dr. Elisabetta Babetto, a ‎research assistant professor at Hunter James Kelly Research Institute, are also authors. Read the study abstract...

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